Viagra vs Cialis: Which ED Drug is Better?

Viagra and Cialis are the 2 most popular and effective medicines for erectile dysfunction. These drugs have a similar effect but at the same time have different active substances. The active substance of Viagra is sildenafil citrate, the active substance of Cialis is tadalafil. Both drugs belong to the same enzyme – PDE-5. To date, the demand for these medicines has increased greatly, and therefore they are used even by young people who want to insure themselves before an exciting date. What is the difference between Cialis and Viagra? Which drug to choose? You will find the answers in this article.

How do these drugs work?

Viagra and Cialis have exactly the same mechanism of action. They are selective inhibitors of the activity of the enzyme phosphodiesterase type 5 (PDE). This enzyme, in turn, inhibits the production of cyclic guanosine monophosphate (cGMP) in smooth muscle tissue, which is formed from guanosine monophosphate (GMP) under the action of nitric oxide (NO). The main function of TSGMP is to relax the smooth muscles of the cavernous bodies of the penis. When the action of PDE is inhibited, much more TSGMP accumulates in the cavernous bodies, their smooth muscles relax much better and much more blood rushes to the penis, causing an erection.

Preparations of this group act selectively in the vascular wall of the penis. They do not cause persistent negative effects during prolonged and regular use. A man is unlike to experience any addiction to pills for erection. However, psychological dependence can occur.

The frequency of side effects depends on the dose of the drug and individual sensitivity).

An absolute contraindication is their intolerance (allergy) and simultaneous intake of organic nitrates (Nitroglycerin, Sustak, Nitrong, Nitrosorbide, etc.). If you combine these pills and organic nitrates, you may experience a sharp decrease in blood pressure.

What is the difference between Viagra and Cialis?

These drugs are taken 15-60 minutes before sexual intercourse. They have differences that you should know.

Viagra has the largest clinical experience because it has been in use since 1998. This drug has helped a greater number of people around the world and it is the most well-studied pill for erection. Viagra should be taken 50-60 minutes before intercourse, it works for about 4 hours, side effects occur quite often.

Cialis is taken 30 minutes before the intended sexual intercourse, fatty foods do not affect its activity, it acts up to 36 hours. Cialis is called the “weekend pill” because one pill allows you to be “in good shape” the whole weekend.

It is also worth noting that these drugs are sold in various dosages.

What to choose?

Since the preparations have different compositions, they have different effects. Cialis is excreted from the body slower than other drugs. Therefore, the main difference is the speed of effect and duration of action.

The most popular medicine is Viagra – doctors prescribe it most often. The action of this medication begins within an hour. The effect lasts for 5-6 hours, therefore, if you plan 1-2 sexual intercourses in the evening, you should choose this drug. However, if a patient takes medicines for hypertension, Viagra is contraindicated to him since the combination of these two drugs causes a strong drop in blood pressure.

Cialis begins to act about an hour after intake, and the effect lasts up to 2 days. Therefore, you can take only 2 pills a week. Cialis is suitable for sexually active men and patients with prostate adenoma since only this drug is approved for use by patients with this pathology. It is also the only drug that can be taken daily (1/4 pill).

Also, when choosing a drug, you should pay attention to the contraindications. They are almost the same, but if the patient is taking antibiotics or antifungal drugs, he cannot use Cialis. For the period of treatment, you’d better refuse from impotence drugs at all, but if you really want to use them, you should use Viagra.

Currently, drugs of this pharmacological group are used not only by important but also by healthy people who want to feel confident during sexual intercourse. For this purpose, you should choose Viagra.

ED drugs are not able to cause an erection, they only contribute to its occurrence by improving blood circulation in the penis. That is, in order for the tablets to work, you need to be sexually aroused.

You also need to remember that impotence is curable, and in some cases, you can even do it without medication. You should consult a neurologist, a psychotherapist, a sexologist and other experts to determine the real causes of the disease and start proper treatment.